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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d2a29e8111e45f5ac66f6703c87c86ac9aad417b80d64d1d60c039c816e579' 
  AND token = 'U9pARjvJP+xaP3gaofal5TGbpviyrYdCmA+QEv0K+vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}