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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ac6d095ee679c8db72ac2859834f87d4057bd6611b133b594ebd41388ef7f4' 
  AND token = 'p59+JuV0LAi9AGL5mAqm/drYtEW0t2z7kJMFu8QrSY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}