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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0fc2784185ffb8e320729e18960f45a3d394d2ec3841301565378c5e39a4d8' 
  AND token = 'f6ywxRZY/g1IjBB77L5Wm451NylPrMeyADlHCvnr+L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}