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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38c91008b6bf31fe00702f1b5bf5163820a5b39a5f8cc21f44c478e24c6f625' 
  AND token = 'ArIbh/uy/wb5Sj2Zwzz39rf6uS+A7guzFMkaSffZTak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}