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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e29c59d99c163e3d0912031bf7182ec45e6fc8f12195dadb5486957ca792b3dd' 
  AND token = 'zV5PeyLzCaxqLiQGzuCTFY0eppVeFSf7KqTxpCYUm1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}