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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9043279525af4073be91a08ab5626cb2e65d93d2c6967068ac6ad3cf03ac349c' 
  AND token = 'TD5b/VNsTVCgTCNUOCo5V+uyEqKyGgJeuX055jV0JxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}