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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45167ea2c9a24e7e13b6d09a4be2ff93ad687cec4b19750f531d51c99643c794' 
  AND token = '3YWFLlp8zLLkIiW1161X2X+t9VK33dKKmgXkJJBLUHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}