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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b0491f96553cb6d111913f0d2a1b5e1aa7d2c1aeacb04cfca9c68232bf1d25' 
  AND token = '+OjXes9A+YSnWD1y8kktLUwildCZNyER/VghdnxtmZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}