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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f821f5be6e0070a954a504bcd06918b6a11166578b6a9bb0ceaf649d3c20b449' 
  AND token = 'OgrP3KOUxLq3YSJTMMOqfK+0YiNx7MZIQ3YzCw/W3lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}