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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb01b5956d9e63b306e91a95b071296c5d340726b6d9a621c375e6b00fa501f0' 
  AND token = 'bNsZkzOhyuhSzukq5DJcrhJoQIfUB9yuErj4mCApwJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}