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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ec11d4abd7715d7467b2369fed427e356aa50ec2a9be31848c4593abcc6938' 
  AND token = 'YaHicrkzj/Y49hD7j/iODkNFzDYDpwz2VVJZ+eCNl/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}