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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201e23de4553c2a21bf8353c734edbae073edb7f5dd7568a81de70848ec36d61' 
  AND token = 'IcmXVDvGqoxpiRMeu2R5v7DPEPi/9X3cGxaP2TF6dkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}