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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37527284b45d4ec6680bc2fc72ec1ca6b89bcb6c35a5ca858f475c8547d56a73' 
  AND token = 'K8JZ/F9mZE+B2JYkUsOXftsTGd5sTTB5N63eqh5lSHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}