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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774a4eb651a9ef26fa62c02a91cdc9a953e9df31d61ae27987df0b58ee198642' 
  AND token = 'uQUqQA6akA5T/LBxdLjzg0iPtDQ9UVaaxo1ICcnCx6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}