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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae7017ecca53988b1c33439a5e86750fea23bbbd3b4081b1dec39d450b298d8a' 
  AND token = 't8qAKk4Gt6bz8RPFXEdg4b809427POEeh1Atz0jMXOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}