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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4b97e38af6b6e484e7bd617a92662503b34961142a60e38e33a5a78159729e' 
  AND token = '5oenARDH/VZQiRE21NIAHs5n6NxnR1tqGoOQ2bE2AYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}