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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b149435d02a1269b8ac47c51c21afe75d52d0111cd1e8d80231739ee02d8425' 
  AND token = 'MRjHZc2lyvA6gjJdRQqCerLHJeYSFWUxbyjJhvlyk5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}