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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8440fab7bbbdf0207155449221b11bcea5528cdb6f4b2eb5da3c7aaaee7f95' 
  AND token = '6sWd+JzGS+2zvovLHPq4aN0ixTBf6S4+V3cOzYxPXdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}