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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7105e6f9581509c1c6cafbcfb49dc5ae37fe8353ff08c9a1efa3178dcf1afada' 
  AND token = 't3jFoZ1kTMy3aMh9BvYGYolKqnQ0Bc34ujpQ3uTzol0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}