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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac2ff314271303e74b5aea431f74808c003862f21945246e61074d203fa36825' 
  AND token = 'W3qTxZcxPUfpxPAJNsFep2S8Aq8544L2rz/GKt6PjYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}