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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353ed36a36552f79de4dc78252c79b6cbdc68842ab3c6d046b1074f603e74381' 
  AND token = '5FMyotDBo2cjOegTh+Z6leYYEULX/XO0hPO7FLLIg80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}