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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc5016bd508387c7d24fcfa002eb2c9d528e6572282e66d4bb261b1d0b442b0' 
  AND token = 'IPHq65bZJHUGzPMBqmC541N7lLlR7n5TWZAJOe1numo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}