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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c516cb104e28030560a9cb2d2073a20189c5fb6b8967fc64f2d510319f44ec0' 
  AND token = 'RWtLQTiY9w1DeNo0O6qDDhOlQ4CR7MZgAx8Kxy6Mz94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}