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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b93e7214ff8d790775a32082ee061dc3c2d6259b75dd1e10b9d9f070c38e18bf' 
  AND token = 'jq03Wj8nMPKwOLW+7b5C/6Ga9o+S/FMqm0YvEE137WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}