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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35f5a9cdc2e4d166e12b5452ff32f7f4f155783749b72baba828e2ff22eddca7' 
  AND token = 'RIgy3EZ1+M4K7Otbv1gj05XmFrIFK3iVbNoh4rk7Yy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}