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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1f6027e66e2d075628fd71f512f0e4bb0440aade7edd60ded4d8beac1f75a2' 
  AND token = 'GCDxoG1xlIOMYjwnJ0nhA8R3DZr4byX4g/tNrIRgMJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}