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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd7e0ac945406268569e4311e07d536d4fac1dcd646711c69a915681c20b5963' 
  AND token = '0UJ1ozGtGoax+QFUaMbHeN9VA6PDSn12WWC5QrAA8gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}