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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6891cabda0e8460174fd1e21f293d298b38b0a88e0f5e4a061beb1dfc48e1548' 
  AND token = 'HxOCG+vhBjbEih7HoSUqqjRzHi304OVxj1g0jTiVqeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}