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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6366562173a4301108f95d550514eabf7489b5aa372ff6d74100229425b5ed8' 
  AND token = 'g8IsnuPEk5LpIirDZrM43cUnMgypqwj9UTX3QT/rXrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}