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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be58e6b8b1354ede5791d3e7c0ba68a0d34debf3da2df533d0395becce0abb6' 
  AND token = 'YjUfv2LlV3vAnjezTZR+PCKUpR97006dKldZTDQGOOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}