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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4974841a103ba3c3dcfdd8b1f4503b394c5ed396ece845111d0f099b274ac5eb' 
  AND token = 'APEqgGdYaNzkGSMDlDj5k6E2OW5Pxi2gu3Pb2GzhOmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}