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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f2258b5c5c94dd302c98d19c8528c9c5296e71857efbd6738efe186b3e34b5' 
  AND token = 'qtBYpVZl6DDAesb7hjcTZQ0aKV3HHSE40HHCx/jCF2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}