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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b1381f49531f3f8d281cc4463c52f179fa09cec3608370d390a225d543e2aa' 
  AND token = 'HRJX+xmMVXeP7MUVtT0Vqz8bXHTVzNbQEsUM3LzMw94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}