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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f226bb64afc1b96abeb27f903bfe320a05681b5ca635aaf3120085e746399b71' 
  AND token = 'myhwCPqzbWZt+8+f9xJOA/R6TLwqOJsNd1iDs5rj9L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}