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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e556c32dc2a8a36aca564d9344bc888698a28022cc918aaf9b3e06ad6170b065' 
  AND token = 'cnUGHoHgD+HpmClN865M0ZnSsE82IN7hsB1aRg21nvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}