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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25fa06278a86e5573bab487c2d510f6c84bf9fa1cd58dc6cb0c00c17465eaca' 
  AND token = 'vGwOz5hY9wHt8avRpz5U4Mj+U9xZQbAf5Kf8rLtVFw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}