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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4429c8c8f4347cbccd4c520329ed69e36a9245c8d10f4c002b6a8610dc1a0c5' 
  AND token = '65I1Gl417bMeJQIDZkHuqpziBNNpVLoNxFp+RCS7gOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}