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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3d8461009b13aa54d3573cdd25fd5c8660bc5082bd666a08d834ebd808f0b4' 
  AND token = '6DFufg9Yg/urdoW/sIpmm+7I3N1FRNOhuNwF9LLSk+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}