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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc8fd835af4b39c8684fcf7d12ff843cf7182a1c07c8cda96c3813c87eb7b70' 
  AND token = 'o2VxvQ9K5CZ7qI4fL4HpC0b/BQXfyf2zGuQtq7pQraI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}