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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81487f57071cc5b4312b0d17a3b0b56d2bc03f08205bebd7446d373bd0a497f' 
  AND token = 'oVVAEzJ3hgyBGKTV6v/akk9WcNEDoDDL/5jJZRRVge0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}