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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6df8224ec55b0b26b1c78a14688bfcf54b34fe08900c49c61c42eff7277102' 
  AND token = 'IkCmcBZTOGmxue8ks6FKKJct6wR2x2dEUmJwgV5c4y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}