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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d9c1b985a63a9fb946c1db37da0e20e764945bcf0b910468a9d369a098fcd3' 
  AND token = 'G/3mDfB26kCsS0Kj54v5OlYpKoUre6PzfsakWve/lcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}