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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca446bddc34237b7a587fc98c2630929ed79eb1bed5a8e8927449725e6808348' 
  AND token = '0KUWO8fxrmn1QoiNurb9KSG38O+UyOyU+1bj5VxWSGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}