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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439b34de12e07b5ca8735781e91f0c09318187838dfc4e13caa7d02ddcbc3e2d' 
  AND token = 'RU/mdl6u+11qnsGLAk2MDHjvXAtjSTYB0HMo5nbw0T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}