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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84163736fc769c1269bfa9f2ff6c10ef13169ac4df416624e79b2adc1adbd990' 
  AND token = 'XUWfzHiFggRI3BYQnWHmckEOtsq4rIPJFUYYMwQtvBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}