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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca35c21216a632506e2e7fe350d733f6238a38972bc9cab9bb75dbaa843f863b' 
  AND token = 'Op39920cxBMpwlupmCMAL+nBsHaOwBwpuM0XIthqzRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}