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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd90421e98438885e302085f7ec6bc7780fb5af09dfc6e9fd1ac26d4ba421e0fd' 
  AND token = 'Y+AnMmZDmYUjM7ur33MJUYh3HeBFMOzmWi04Y97jYVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}