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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9f728597a67428739c2bd584906d8bf6bb61259af42a8a8f2fd5d7bcefc530' 
  AND token = 'ztM0wcvIvnzeo+OD5eMZ1QHROfu104EiFCuZKS0F6oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}