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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e174c03641f01c06cd6c98a623936ca5d5d4a9c2094241b4da52936f80500a4' 
  AND token = 'Edifd2rHLJ7k6WTAnooL0OBAnW05kRrAdE9MzT/cqLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}