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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cda5dd4b995370c716f2ed1100141ee81492a559641490a21c80ee7bd07256c' 
  AND token = 'cvLUM5Wah+CR7YL2FynXNtggCoAtN1JC/PyxNXZQ4XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}